How do electrical signals propagate or dissipate through a dendritic tree?

Feb 15, 2016

In computational neuroscience, what is an integrate-and-fire neuron? How does it differ from a real neuron?

Jan 27, 2016

What is the mechanism of inactivation of voltage-gated channels that results in transient currents in response to sustained membrane depolarization?

Jan 26, 2016

How do ionotropic and metabotropic receptors transduce detection of an extracellular signal into a change in neural activity? Give examples and describe similarities and differences between the receptor classes.

Jan 26, 2016

How do K+ channels pass K+ and Rb+ but exclude Na+ and Cs+?

Jan 26, 2016

What is the structure and mechanism of the voltage sensing apparatus of voltage-gated channels?

Jan 25, 2016

What is the ionic basis of the basic features of an action potential?

Jan 21, 2016

What is the ionic basis of the resting potential? Draw an equivalent circuit model of the resting membrane.

Jan 13, 2016

What is population coding? Describe the population coding model proposed by Georgopoulos in the 1980s for M1 control of arm direction.

Apr 12, 2016

Draw a neural circuit representing feedforward inhibition and one representing lateral inhibition. What are the major computational roles of these circuit motifs?

Feb 10, 2016

Give an example of a specific, well-studied neuronal microcircuit and describe how it performs a specific calculation.

Feb 7, 2016

What is the principle of sparse coding? Explain its relation to other coding schemes such as dense codes or grandmother cells, and give examples of each in the nervous system. Why is sparse coding more common higher in sensory hierarchies?

Jan 14, 2016

Describe the differences between rate coding and temporal coding, and give examples of each in the nervous system.

Jan 14, 2016

What is a central pattern generator? Choose a well-studied CPG and describe how it functions.

Apr 11, 2016

How is M1 organized? What features of movement are represented in spiking of M1 neurons?

Apr 10, 2016

Describe the key cortical areas and subcortical structures of the motor system. Give an example of how these components contribute to the performance of a simple motor task such as reaching and how they contribute to the performance of a skilled action like playing the piano.

Apr 9, 2016

Describe the major components of a generic brain-machine interface for restoring motor function in a paralyzed person.

Feb 12, 2016

What is the function of the cerebellum in motor control? Describe the basic microcircuit for integrating sensory cues and motor control signals in the cerebellum.

Feb 11, 2016

What are the basal ganglia and their major component circuits? What role do the basal ganglia play in movement and choice of movements?

Feb 9, 2016